Idiopathic destructive thyroiditis resulting in fibrosis of thyroid and adjacent neck. Clinically this is a hard, palpable goiter, which could cause pain, compressive symptoms, and affect adjacent structures as the parathyroid glands, musculature in the neck and cause vocal cord paralysis. We report the case of 48year old woman with riedels thyroiditis who has presented unusual course of disease with nonspecific cervical discomfort, though as with no pain andor no compression symptoms. Riedel thyroiditis, also called struma fibrosa, or ligneous thyroiditis, extremely rare form of chronic inflammation of the thyroid gland, in which the glandular tissues assume a densely fibrous structure, interfering with production of thyroid hormone and compressing the adjacent trachea and esophagus. It is now believed that riedel s thyroiditis is one manifestation of a systemic disease that can affect many organ systems called igg4related disease. Riedel s thyroiditis is a rare disorder of unknown etiology and may be seen isolated or as a part of multifocal fibrosclerosis. Thank you for your interest in spreading the word about the bmj.
The term thyroiditis encompasses a diverse group of disorders characterized by some form of thyroid inflammation. Riedels thyroiditis may resemble an infiltrating carcinoma, i therefore assume and i hope, with all the medicals thyroidcancer was investagated and ruled out. The four types of thyroiditis are acute or suppurative typically a shortterm condition caused by infection, subacute, riedels, and hashimotos. The coexistence of both diseases in a patient is rare and is probably coincidental in this instance. A fifty two year old female underwent attempted thyroidectomy for a progressively enlarging cervical swelling. Antithyroid drugs carbimazole, methimazole and propylthiouracil are initial treatment of choice in graves disease. Started in 1995, this collection now contains 6767 interlinked topic pages divided into a tree of 31 specialty books and 732 chapters. Pdf riedel thyroiditis rt is an uncommon form of chronic thyroiditis in which the thyroid gland is replaced by fibrous tissue. A misdiagnosed riedels thyroiditis successfully treated.
They include conditions that cause acute illness with severe thyroid pain eg, subacute thyroiditis and infectious thyroiditis and conditions in which there is no clinically evident inflammation and the illness is manifested primarily by thyroid dysfunction or. So, riedels thyroiditis is a condition where there is inflammation of the thyroid gland, which slowly causes fibrous tissue to replace the normal thyroid tissue. There are many possible causes of thyroiditis see thyroiditis brochure. In the united states and other countries where the ordinary diet provides sufficient iodine median urinary iodine levels, 100 g. It is often a multiorgan disease affecting pancreas, liver, kidney. It is often a multiorgan disease affecting pancreas, liver, kidney, salivary and orbital tissues and retroperitoneum. Thyroid riedel thyroiditis riedel thyroiditis is an extremely rare as prevalent as hashimotos fibroinflammatory condition of the thyroid, first described in the mid to late1800s and now thought to be igg4 related. Riedel s thyroiditis synonyms, riedel s thyroiditis pronunciation, riedel s thyroiditis translation, english dictionary definition of riedel s thyroiditis.
Case report with special reference to preoperative diagnosis. Riedels thyroiditis is an often disabling disease with clinical and histologic similarity to several other fibrous inflammatory disorders. Reports about imaging features of riedel s thyroiditis are limited in the radiologic literature. Riedels thyroiditis is a rare disorder of unknown etiology and may be seen isolated or as a part of multifocal fibrosclerosis. At operation the thyroid gland was extensively fibrosed and not resectable, frozen section showed fibrous replacement.
Thyroid uk other thyroid disorders riedels thyroiditis. Moreover, the electronic medical files of all patients seen at the. Riedels thyroiditis is a rare inflammatory process involving the thyroid and. It is now believed that riedels thyroiditis is one manifestation of a systemic disease that can affect many organ systems called igg4related disease. Reports about imaging features of riedels thyroiditis are limited in the radiologic literature. Herein, we describe our results of studies on genes expression levels in riedels thyroiditis. Riedels thyroiditis, is a chronic form of thyroiditis. In this article, we describe an unusual case of riedels thyroiditis and discuss its imagery and pathology. Usually this is a part of a multifocal, systemic, fibrotic syndrome which includes biliary tract sclerosis, sclerosing cervicitis, and sjogren sydrome. Riedels thyroiditis is a rare chronic inflammatory disease of the thyroid gland first recognized by bernhard riedel in 1893. Riedels thyroiditis article about riedels thyroiditis by. This feature differentiates rt from other inflammatory or. Riedel thyroiditis definition of riedel thyroiditis by. It is often a multiorgan disease affecting pancreas, liver, kidney, salivary and orbital tissues and.
Diagnosis of riedels thyroiditis requires histopathological confirmation, but due to. A number of hypotheses have been proposed regarding etiology and pathogenesis of riedels thyroiditis. In this article, we describe an unusual case of riedel s thyroiditis and discuss its imagery and pathology. The disease may be associated with subacute and chronic thyroiditis, thus some authors proposed the, so called. There is a paucity of robust epidemiological data because the worlds literature consists primarily of case reports and small case series.
Extensive stony hard fibrosis involving a goitrous thyroid gland and infiltration into adjacent muscle and other structures, obliterating tissue planes at surgery. Although riedels thyroiditis and the fibrosing variant of hashimotos thyroiditis were once considered morphologic variants of the same disease, since the 1970s these diseases have been considered as distinct clinicopathologic entities. Riedels thyroiditis riedels thyroiditis is a very rare form of thyroid disease which causes a dense fibrosis scarring of the connective tissue that replaces normal thyroid tissue. Riedels thyroiditis synonyms, riedels thyroiditis antonyms. Ideal sources for wikipedia s health content are defined in the guideline wikipedia.
In order to clarify the clinical and pathologic features of this rare disorder, a recent case of riedels thyroiditis is presented, 6 additional cases from the surgical pathology files of the. Few epidemiologic studies of sat have been reported. It presents with firm rock hard, fixed, and usually painless enlargement of the thyroid often presenting. Synonyms for riedel s thyroiditis in free thesaurus. By continuing to use our website, you are agreeing to our use of cookies. The term thyroiditis refers to inflammation of the thyroid gland. Epidemiology and demographics riedels thyroiditis is a rare disease with an approximate incidence. The thyroid becomes enlarged, often asymmetrically, to form a firm, hard mass of scar. Genetic background of riedels thyroiditis remains unknown. Hashimotos thyroiditis, also known as chronic lymphocytic thyroiditis, is the most common cause of hypothyroidism in the united states.
Riedels thyroiditis, also called riedels struma is a chronic form of thyroiditis it is now believed that riedels thyroiditis is one manifestation of a systemic disease that can affect many organ systems called igg4related disease. Risk factors for chronic autoimmune thyroiditis such as hashimotos disease and other forms of lymphocytic thyroiditis are both genetic and environmental. Thyroid riedel thyroiditis riedel thyroiditis is an extremely rare as prevalent as hashimoto s fibroinflammatory condition of the thyroid, first described in the mid to late1800s and now thought to be igg4 related. Riedel thyroiditis is a very rare form autoimmune thyroiditis. We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. Riedels thyroiditis is a rare type of chronic thyroiditis, associated with fibroinflammatory process and invasion into surrounding tissues, leading to compressive symptoms. Riedels thyroiditis is a form of thyroiditis that occurs in middle aged or elderly women. In mri study reveals riedels thyroid to be hypodense. For example, hashimoto s thyroiditis is the most common cause of hypothyroidism in the united states. This fibrotic process spreads to tissue in the neck outside the thyroid capsule.
Riedels thyroiditis is a chronic sclerosing replacement of the gland that is. Riedels thyroiditis is characterised by chronic inflammation, which causes dense fibrosis in the thyroid gland. Pdf a 46yearold woman with clinical diagnosis of riedels thyroiditis was admitted to our department, presenting with dyspnea, dysphagia, fatigue. Riedels thyroiditis american journal of clinical pathology. Blood test for antithyroid antibodies is positive in many cases of riedels thyroiditis. Riedels thyroiditis is a rare benign pathology of unclear etiology, characterized by a densely fibrotic inflammatory process involving the thyroid gland and the adjacent neck tissues 1.
Riedels thyroiditis, riedel thyroiditis, fibrous thyroiditis. Riedels thyroiditis on the web most recent articles. Synonyms for riedels thyroiditis in free thesaurus. Corticosteroid therapy in riedel s thyroiditis 819 1 hayid. The fibrotic tissue extends beyond the capsule of the gland into the surrounding structures of the neck and may develop sufficiently to compress the trachea. The exact cause of riedels thyroiditis remains unknown, and no specific treatment is available beyond limited resection of the thyroid. Surgical treatment alone is often unsatisfactory in permanently alleviating airway compression, dysphagia, neck. Thyroiditis is a general term that refers to inflammation of the thyroid gland.
In the united states and other countries where the ordinary diet provides suf. He speculated there was a factor that caused the lymphocytic expansion of the thyroid size, naming it after. Pain is a symptom and i believe, as well as all the rest that you have mentioned, classic to cancer. Thyroiditis includes a group of individual disorders causing thyroidal inflammation but presenting in different ways. Most recently all these pathologies are considered as manifestations of the same pathology known as igg4. It is important to distinguish riedels thyroiditis from thyroid carcinoma. This article is from journal of the korean surgical society, volume 82. A thyroid biopsy with histologic features of both riedels.
Conjugate riedel deformation band shear zones george h. Pdf current concepts on riedel thyroiditis researchgate. We describe herein ct and mr imaging features of riedel s thyroiditis in a case of. Clinically this is a hard, palpable goiter, which could cause pain, compressive symptoms, and affect adjacent structures as the parathyroid glands, musculature in the neck and cause. The patient was given a short course of postoperative corticosteroid therapy and was maintained on thyroid replacement therapy. She suffered from bilateral neck pain, which radiated to both lower jaws. With riedels thyroiditis, thyroid refers to the thyroid gland, and itis means inflammation. Riedels thyroiditis treated with tamoxifen article pdf available in croatian medical journal 442. Acute and subacute, and riedels thyroiditis endotext ncbi. Riedel s thyroiditis is a rare chronic inflammatory disease of the thyroid gland first recognized by bernhard riedel in 1893. Case report open access riedel s thyroiditis a case. In order to clarify the clinical and pathologic features of this rare disorder, a recent case of riedels thyroiditis is presented, 6 additional cases from the surgical pathology files of the cleveland clinic foundation are reported, and the 178 cases.
It is precisely the observational nature of sat therapy combined with the use of glucocorticoids which make it so critical to definitively rule out the bacterial etiology of ast in the patient presenting with a painful thyroid. Epidemiology and demographics riedel s thyroiditis is a rare disease with an approximate incidence of 1. Riedels thyroiditis, known as invasive fibrous thyroiditis, is a very rare form of chronic thyroiditis. Riedels thyroiditis an overview sciencedirect topics. Riedels thyroiditis is a rare benign pathology of unclear eti. Riedel s thyroiditis is a chronic sclerosing replacement of the gland that is exceedingly rare. A family history of the condition or a history of autoimmune disease increases risk. Corticosteroid therapy in riedels thyroiditis 819 1 hayid. For information on thyroid patient support organizations, please visit the patient support links section on the ata website at. Riedels thyroiditis is exceedingly rare, occurring in some series one 50th as frequently as hashimotos thyroiditis 1115. Abstractriedels thyroiditis is an extremely rare disease that is difficult to diagnose. The process extends to adjacent structures, making any surgical intervention very difficult and potentially harmful.
The exact cause of riedels thyroiditis remains unknown. A rare form of thyroiditis characterized by fibrotic destruction of the thyroid gland. The exact cause of riedel s thyroiditis remains unknown, and no specific. In order to clarify the we use cookies to enhance your experience on our website. Riedels thyroiditis definition of riedels thyroiditis by. Mar 07, 2017 riedel thyroiditis, or riedel s thyroiditis rt, is a rare, chronic inflammatory disease of the thyroid gland characterized by a dense fibrosis that replaces normal thyroid parenchyma. It is important to distinguish riedel s thyroiditis from thyroid carcinoma. It is now believed that riedels thyroiditis is one manifestation of a systemic disease that can affect many organ. The diagnosis of hashimotos thyroiditis may be made when patients present with symptoms of hypothyroidism, often accompanied by a goiter an enlarged thyroid gland on physical examination, and laboratory testing of hypothyroidism, which is an elevated thyroid stimulating. Riedel thyroiditis, or riedel s thyroiditis rt, is a rare, chronic inflammatory disease of the thyroid gland characterized by a dense fibrosis that replaces normal thyroid parenchyma. The exact cause of riedels thyroiditis remains unknown, and no specific. It is clear that various reports document positive results with other. Riedel s thyroiditis, also called riedel s struma is a chronic form of thyroiditis.
We present a case of riedels thyroiditis in a 52yearold female with past history of hashimotos thyroiditis. Riedel thyroiditis, or riedels thyroiditis rt, is a rare, chronic inflammatory disease of the thyroid gland characterized by a dense fibrosis that replaces normal thyroid parenchyma. Riedel thyroiditis is a very rare form of autoimmune thyroiditis. Hashimotos thyroiditis also called chronic lymphocytic thyroiditis is the most common of the four types of thyroiditis, and is probably the most common type of thyroid disorder. Jan 29, 2018 riedels thyroiditis fibrous thyroiditis, rt is an extremely rare form of thyroiditis, leading to a gradual parenchymal transformation to connective tissue. The trip database provides clinical publications about. In carcinoma of thyroid gland, it appears hyperdense. It is hard to make the diagnosis without surgical biopsy. Treatment hashimotos thyroiditis with hypothyroidism is best treated with lthyroxine replacement.
Riedel thyroiditis redel, a rare fibrous induration of the thyroid gland, with adhesion to adjacent structures, which may cause tracheal compression. Since riedels thyroiditis is a rare disease, there is lack of research for specific therapy. Riedel s thyroiditis, is a chronic form of thyroiditis. It is sometimes considered as a manifestation of a wider systemic disease with fibrosis of the retroperitoneum, mediastinum, as well as lymphocytic infiltration of extraocular orbital muscles, salivary and lacrimal glands 4. Riedel s thyroiditis is a form of thyroiditis that occurs in middle aged or elderly women. Riedel s thyroiditis is a rare benign pathology of unclear etiology, characterized by a densely fibrotic inflammatory process involving the thyroid gland and the adjacent neck tissues. The fibrotic process invades adjacent structures of the neck and extends beyond the thyroid capsule. Riedels thyroiditis fibrous thyroiditis, rt is an extremely rare form of thyroiditis, leading to a gradual parenchymal transformation to connective tissue. We describe herein ct and mr imaging features of riedels thyroiditis in a case of.
441 1112 1365 1092 1265 131 824 469 865 327 992 291 163 649 1228 103 1361 879 183 1060 769 818 1505 1146 535 1270 419 553 509 645 270 33 950